Conventional magnetic resonance imaging performed around term-equivalent age (TEA-MRI) or even soon after birth has been shown to be superior to cUS in detecting more subtle brain lesions. , and an unfavourable cognitive and motor outcome. or cystic periventricular leukomalacia (PVL) according to de Vries et al. Significant associations have been reported between severe cUS abnormalities, such as germinal matrix-intraventricular hemorrhage (GMH-IVH) grade III or IV according to Papile et al. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.ĭuring the last decades, several neuroimaging modalities have been introduced to evaluate the preterm brain during the neonatal period in order to improve prediction of developmental impairments.Ĭranial ultrasound (cUS) has proven to be an easily accessible neuroimaging technique, which can be performed at the bedside to detect a variety of brain lesions in the preterm infant. BK was supported by ZonMW, The Netherlands Organization for Health Research and Development, project 94527022. All relevant data are within the paper.įunding: MJB was supported by Alexandre Suerman Stipendium, University Medical Center Utrecht, The Netherlands. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: The authors confirm that all data underlying the findings are fully available without restriction. Received: JAccepted: SeptemPublished: October 20, 2014Ĭopyright: © 2014 Brouwer et al. PLoS ONE 9(10):Įditor: Pierre Gressens, Robert Debre Hospital, France (2014) Sequential Cranial Ultrasound and Cerebellar Diffusion Weighted Imaging Contribute to the Early Prognosis of Neurodevelopmental Outcome in Preterm Infants.
Citation: Brouwer MJ, van Kooij BJM, van Haastert IC, Koopman-Esseboom C, Groenendaal F, de Vries LS, et al.
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